Fembot - Female Robot
A movie clip of a fembot that looks really real.
I'm gonna save up and buy me one in 2020, when you can't distuingish them anymore from biological women. ;)
About upcoming technologies such as nanotechnology, biotechnology, robotics and artificial intelligence. All of these are accelerating exponentially. The implications are vast.
A movie clip of a fembot that looks really real.
I'm gonna save up and buy me one in 2020, when you can't distuingish them anymore from biological women. ;)
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Tuesday, October 10, 2006
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Fantastic animation of the insides of a cell. This is just an animation. But there is no reason it could not be a simulation in the future. And sophisticated simulations of cells are powerful tools that will speed up medical research by orders of magnitudes. This will have a great impact on public health. We will live longer and more healthy because of it.
Robot cars will race in real traffic
The first 11 teams for a race in which robot cars will jostle with real ones along mocked-up city streets have been announced. The teams must construct autonomous vehicles to navigate an unfamiliar urban environment in the shortest time possible.
The X Prize Foundation, sponsor of a widely noted 2004 award for developing a reusable rocket suitable for private space travel, says it is now teaming with a wealthy Canadian geologist to offer $10 million to any team that can completely decode the genes of 100 people in 10 days.
He forecast that, within five years, "truth predictor" software would "hold politicians to account". Voters would be able to check the probability that apparently factual statements by politicians were actually correct, using programmes that automatically compared claims with historic data, he said.
Beaming people in "Star Trek" fashion is still in the realms of science fiction, but physicists in Denmark have teleported information from light to matter bringing quantum communication and computing closer to reality.
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Saturday, October 07, 2006
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PC World came up with this list of 100 forecasts, of which I have listed an interesting selection for your reading pleasure.
Accurate Speech Recognition
Though the vendor of the Dragon NaturallySpeaking speech-recognition program claimed an accuracy of 99 percent, in our recent tests the application managed an accuracy of only about 96 percent--not bad, but not good enough. We don't need perfection, but we are looking forward to a speech-recognition system that is fast and accurate enough to replace a keyboard for writing.
Memory That Doesn't Forget
Your existing PC memory gets amnesia when the system power goes off, but NRAM (nanotube nonvolatile RAM) remembers everything, and is as fast as modern memory. With NRAM, your PC could turn on and off immediately, dispensing with all of its tedious booting up and shutting down.
Nanotube Heat Sinks
Modern PC components produce a lot of heat, but carbon nanotube heat sinks will conduct that heat away better than existing metal ones do. See "The Future of Nanotech" for more details on how nanotechnology will revolutionize computing.
Quad-Core Processors
Dual-core processors have given PCs a big speed boost, but the advances won't stop there. Quad-core systems from Intel will arrive before the end of the year, and AMD's quad-core chips will hit the market in mid-2007.
TVs Out of Thin Air
The Helio display can create a TV out of nowhere, projecting an image onto a curtain of compressed air. Right now it is prohibitively expensive (around $20,000), but the price will fall as the technology matures.
One-Box Surround Sound That Works
If products such as Yamaha's promising $1700 YSP-1100 Digital Sound Projector continue to improve (and become affordable), complex surround-sound wiring could become a thing of the past. The YSP-1000 uses 40 beam drivers to focus surround precisely, creating a convincing surround effect out of just one box.
2015's New Mainstream Camera: 20 Megapixels
The price of digital cameras will continue to slide, while the resolution will continue to increase. Analyst Ron Glaz of IDC thinks that shoppers will be able to buy a 10-megapixel camera for less than $300 by the end of 2007, and a 20-megapixel camera for less than $300 by 2015.
A Shift From 2D Photos to 3D Environments
The increased processing power of computers allows for new ways to handle images. The Photosynth project from Microsoft, for instance, takes a group of 2D photographs and transforms them into a 3D environment that provides a whole new way to browse pictures.
Console Wars 2012
Despite Sony's and Microsoft's protests that this year's game consoles will last longer than previous ones, game consoles have five-year life spans. So, in the December 2012 issue of PC World, we'll be reviewing the new PlayStation 4 and Xbox 720 game consoles, which will have photorealistic 3D games and high-def movies streamed over the Internet.
Smarter Games
The advent of multicore processors gives game programmers a lot more processing power to create smarter adversaries in games: For example, one core can be dealing with running the game, while the other is running an artificial intelligence (AI) routine that creates hordes of smart enemies. And your opponents won't just sit and wait for you, either--they'll hunt you down.
Robots, Part 1: Death to Allowances
Teenagers' options for earning money at home will shrink greatly as single-duty robots take over household chores. A 2004 United Nations report on World Robotics predicts that prices for grass-cutting, pool-cleaning, and window-washing robots will become affordable by 2007, and some 4 million robots will be in use by the end of that year.
Robots, Part 2: Hope It's Not the Terminator
While the world now has a robot that can run 4 miles per hour--Honda's ASIMO--Stephen Keeney, the ASIMO project leader, hopes that by 2017 folks will see the first application of a truly humanoid robot.
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Wednesday, October 04, 2006
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Havok 4.0
It's at least as impressive as the Intel Quad Core Alan Wake game demo that I posted not too long ago.
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Wednesday, October 04, 2006
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Twenty of the coolest recent technological developments, listed here at Our Technological Future for your leisure.
The first link (Intel Quad Core Demo) is a must-see.
Seriously. You will never forgive yourself if you don't click it.
Technolinks:
Intel Quad Core Demo (never before seen graphics and physics)
Technological nirvana
PayPal Founder pledges $3.5 Million to antiaging research
Antisocial robots go to finishing school
The bootless PC and terabytes on a dime
Call centers might be able to teach "chat bots" a thing or two about passing the Turing Test
A Question of Mind Over Matter
Take an Interactive Bionics Tour
An Artificial Heart That Doesn't Beat
Quantum Leap In Protein Folding Calculations
Intercytex pushes ahead with trials for wrinkles, baldness treatments
Stem cells help rats retain their vision
Relativity drive: The end of wings and wheels?
Internet's future in 2020 debated
Honda unveils diesel system to rival gasoline cars
What if Bionics Were Better?
Grow Your Own Limbs
Man Builds 105 MPG Car
New Power Suit Amplifies Human Strength
Roll-up screens 'moving closer'
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Sunday, October 01, 2006
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I have compiled a list of twelve recent and exciting technology developments. I recommend clicking the source-links to see the pictures and movieclips that go with them.
Solid to Liquid - The Story of Armor
This is any science fiction enthusiasts dream come true! Soldiers of The United States Army are testing liquid armor. This armor will enhance Kevlar, the fibre-based armor that is 5x stronger than steel.
Now, Mitchell can peel a banana in a less simian posture. All she has to do is place her prosthetic left arm next to the banana and think about grabbing it. The mechanical hand closes around the fruit and she's ready to peel.
Physicists in the US have taken another step towards the dream of a quantum computer by entangling two superconducting quantum bits (or qubits) for the first time.
Can we prove realms exist beyond our plane ... or ‘brane’?
Large Hadron Collider likely to shed light on dark matter, dark energy
Though you can’t see it, nanotechnology is everywhere now, expanding the utility and appeal of basic products from cosmetics to all types of clothing. Below is a Top 10 list of the products you might least expect to employ this advanced technology.
Click link to see the movieclip.
"The 3-D maneuverability of the Frisbee-UAV [unammned aerial vehicle] will provide revolutionary tactical access and lethality against hostiles hiding in upper story locations and/or defiladed behind obstacles," the company promises.
Snaggle-toothed hockey players and sugar lovers may soon rejoice as Canadian scientists said they have created the first device able to re-grow teeth and bones.
A small but passionate group of doctors say that electricity applied deep in the brain can jolt patients out of irreversible comas. That's when the real problems begin.
Scientists claim they are near to finding a therapy that could cure Aids and cancer. So how real is this new medical dawn?
Who would pay millions of dollars for a vehicle with no steering wheel, seats, or a gas pedal? The U.S. Military, whose unmanned "Crusher" robot can drive itself. This ScienCentral News video explains.
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Sunday, September 17, 2006
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Scientists Eye Embryonic Stem Cell Therapy for 2012.
CHEJU _ Cheju National University plans to set up a large biology research center with the aim of starting to use human embryonic stem cells in actual therapy around 2012.
Koh Choong-suk, president of the scenic Cheju Island-based university, yesterday unveiled the project that will be spearheaded by illustrious embryologist Park Se-pill.
``We recruited Park as the head of the stem cell center to be established at our university, and seek to hire about 20 more researchers and experts,'' Koh told a press meeting at the university.
``Under the stewardship of Park, we believe the lab will be able to use embryonic stem cells in therapy by 2012,'' Koh added.
Researchers from the National Cancer Institute on Thursday reported they have successfully treated two patients with advanced cancer using gene therapy.
Two men, both with the rapidly growing skin cancer melanoma, were given immune-system cells taken from their own blood and engineered to attack their tumors. They are alive, with no evidence of cancer, 18 months later. Fifteen other patients who got the same treatment died.
The senior author of the study and others cautioned it would take several years to translate the treatment into a practical therapy.
The report, published online by the journal Science, is the latest result of a 30-year effort by Dr. Steven Rosenberg to find ways to manipulate the human immune system to fight cancer.
Superimposing computer-generated images over real scenes can dramatically improve the way people with visual impairment use their sight, say US researchers.
That conclusion is the result of tests of a so-called augmented-reality system on patients with tunnel vision, a condition which narrows a person’s field of view.
University of Arizona physicists have discovered how to turn single molecules into working transistors. It's a breakthrough needed to make the next-generation of remarkably tiny, powerful computers that nanotechnologists dream of.
A research team in Sydney has created molecules that mimic those in plants which harvest light and power life on Earth.
“A leaf is an amazingly cheap and efficient solar cell,” says Dr Deanna D’Alessandro, a postdoctoral researcher in the Molecular Electronics Group at the University of Sydney. “The best leaves can harvest 30 to 40 percent of the light falling on them. The best solar cells we can build are between 15 and 20 percent efficient, and expensive to make.”
Genomic technologies may have the potential to alleviate food insecurity and food shortages around the world. Researchers believe that biotechnology has the potential to improve the nutritional content of food crops and, crucially, resistance to insects and disease. This could lead to improved yields of food crops for both human and animal consumption. Researchers are also working on 'molecular farming' – production of pharmaceutical products in plants, with the potential to revolutionise vaccination procedures.
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Sunday, September 03, 2006
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Upcoming drug revolution takes a quantum leap.
British scientists have found that enzymes cheat time and space by quantum tunnelling - a much faster way of travelling than the classical way - but whether or not perplexing quantum theories can be applied to the biological world is still hotly debated.
Until now, no one knew just how the enzymes speed up the reactions, which in some cases are up to a staggering million times faster.
"Our research has shown at an atomic level how enzymes act as catalysts," said Nigel Scrutton, lead researcher at the University of Manchester, whose team published their work in the U.S. journal, Science, on April 14.
Just how these enzymes speed up reaction rates compared with uncatalysed reactions remain controversial among scientists, but such insights of the underpinnings of enzyme behaviour have begun.
"Enzymes are central to the existence of life because most chemical reactions in our cells would take place too slowly or produce a difference outcome without their involvement," he said.
Without enzymes, we'd wither away or be riddled with disease.
As biological molecules, the enzymes work to lower the energy needed for a reaction to occur. Although enzymes act as catalysts, they are often affected by other molecules. Therefore, when drugs are made, they are designed to act as enzymes inhibitors to stop the reactions from occurring.
"The findings are a radical departure from the traditional view of how they work and might explain why attempts to make artificial enzymes have so far been disappointing," he said.
But now that researchers know enzymes can quantum tunnel, better drugs can be designed leveraging this knowledge.
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Sunday, August 27, 2006
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Just found this on YouTube.
The robot looks so real, it's bizarre.
This made it much easier for me to see how robots may one day intermingle with us without us being able to clearly distuingish between robots and biological humans.
Einstein Robot.


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Sunday, August 27, 2006
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Embryonic stem cells without embryo death.
You don’t have to destroy an embryo to create stem cells for medical research. An American biosciences company has succeeded in deriving the cells from embryos without killing them, raising hopes that President Bush will reconsider his veto on federal funding for such work.
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Lanza hopes that because the method does not involve destroying embryos, it will lead to the lifting of the veto on federal funding for stem cell research. “We need to jump-start the field – it’s been crippled by a lack of funding,” he says. “This will hopefully solve the political impasse and bring the president on board, as no embryos will be harmed with this method.”
Once we understand how the mind operates, we will be able to program detailed descriptions of these principles into inexpensive computers, which, by the late 2020s, will be thousands of times as powerful as the human brain—another consequence of the law of accelerating returns. So we will have both the hardware and software to achieve human-level intelligence in a machine by 2029. We will also by then be able to construct fully humanlike androids at exquisite levels of detail and send blood-cell-size robots into our bodies and brains to keep us healthy from inside and to augment our intellect. By the time we succeed in building such machines, we will have become part machine ourselves. We will, in other words, finally transcend what we have so long thought of as the ultimate limitations: our bodies and minds.
Nanosolar is a company based in Palo Alto, California, which uses an innovative technique to produce a kind of "solar film". To make the film, Nanosolar prints CIGS (copper-indium-gallium-selenium) onto a thin polymer using machines that look like printing presses. There is no costly silicon involved in the process, and, ultimately, a solar cell from Nanosolar will cost about one-fifth to one-tenth the cost of a standard silicon solar panel. Nanosolar is only a few years old, but it has laid plans to take on multinational corporations, such as BP and Sharp, in the solar industry.
First it was the typewriter, then the teleprinter. Now a US news service has found a way to replace human beings in the newsroom and is instead using computers to write some of its stories.
Thomson Financial, the business information group, has been using computers to generate some stories since March and is so pleased with the results that it plans to expand the practice.
The computers work so fast that an earnings story can be released within 0.3 seconds of the company making results public.
Ditto's chip is like the microelectronic version of a stem cell: It's a device that can assume all sorts of different functions. But a chaotic chip goes one step further: It can morph over and over again. For computer design, this has huge implications. In a traditional chip, the basic elements, called logic gates, are hardwired to perform a single, specific task. In a chaotic chip, each logic gate can be converted on the fly to perform any function.
What this means is that computers will no longer need separate, costly chips for the CPU, memory, video RAM, graphics accelerators, arithmetic processing units, and so on. Instead, one chip will convert itself to whatever functions the software needs at a given moment.
I entered a conference room in Manhattan and a woman on the TV tossed a handful of rose petals out of the screen, where they floated in the air before my eyes.
At least, that's what I saw. In truth, the image resided on a perfectly flat, 42-inch LCD screen. But the 3-D illusion was fully believable, and I didn't have to wear a dorky set of polarizing glasses.
A new line of 3-D televisions by Philips uses the familiar trick of sending slightly different images to the left and right eyes -- mimicking our stereoscopic view of the real world. But where old-fashioned 3-D movies rely on the special glasses to block images meant for the other eye, Philips' WOWvx technology places tiny lenses over each of the millions of red, green and blue sub pixels that make up an LCD or plasma screen. The lenses cause each sub pixel to project light at one of nine angles fanning out in front of the display.
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Thursday, August 24, 2006
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Govt to back intelligence robot development.
Japan's Ministry of Economy, Trade and Industry plans to begin assisting the development of next-generation intelligence robots in fiscal 2007 with the aim of commercializing them in 2015, Jiji Press learned Thursday.
The ministry is set to seek 2.1 billion yen in related funds as part of its budget request for the fiscal year that starts next April, and will assist the development of basic technologies in the next five years, informed sources said.
Intelligence robots are capable of recognizing sounds and images through sensors and of automatically analyzing the obtained information to determine their actions. Conventional industrial robots require input work patterns before they can operate.
For the government-funded development project, the ministry will seek the participation of universities and manufacturers that conduct research into artificial intelligence and sound and image recognition technologies, the sources said.
It hopes to commercialize the newly developed robots by 2015. The robots will include "cleaning robots" that, equipped with the plan of a building, will be able to choose the most appropriate routes to reach areas that need cleaning, and "guide robots" capable of communicating with humans through advanced voice and image processing technologies.
Reflecting a surge in the number of industrial robots in the past 10 years, there are some 840,000 robots operating at present across the globe.
In Japan, the market for industrial robots is expected to expand to around 3 trillion yen over the next decade.
Against this backdrop, the government acknowledges that intelligence robots constitute one of its core strategies for economic growth.
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Sunday, August 20, 2006
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IBM researchers in Zurich, Switzerland, have demonstrated a single-molecule device capable of repeatedly storing and retrieving data.
Described in the Aug. 4 issue of nanotech journal Small Times, the device is a surprisingly simple organic compound that can be set to high or low resistance through electrical pulses. In the lab, it reliably retained its ability to change states over many hours and more than 500 tests, which the researchers described in the paper as "a remarkable result for a single-molecule system."
"Right now, we are concentrating on understanding the relationship between the design of the molecular system and the electrical properties measured," researcher Heike Riel told ZDNet UK. "Our next steps are to investigate the mechanism responsible for switching."
The molecule at the heart of the system, BPDN-DT, was designed by professor James Tour and co-workers at Rice University in Houston and is one of a class of compounds called Tour wires. Although it was specifically synthesized to operate in this and other devices--it has also been used in a single molecule transistor--there is still considerable debate as to how it works and what characteristics any potential commercial application may have.
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At about 1.5 nanometers long, the molecule is less than a hundredth of the size of current silicon memory elements. It is widely accepted in the industry that current progress in silicon will become economically more difficult below 20nm, with fundamental physical limits being reached below 10nm. IBM says it sees molecular computing as one way of pushing past this barrier, as well as semiconducting wires, carbon nanotubes and spintronics.
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Tuesday, August 15, 2006
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Working four to six hours a day is the key to happiness, according to a new report.
In the quest for money and status, Australians are among the hardest workers in the world.
But Sydney University academic Dr Caroline West says while work delivers self-esteem, income and social ties, more than four to six hours a day will bring anxiety, exhaustion and a poor quality of life.
"We've structured our lives so the majority of our waking life is devoted to work, which might bring us more money but doesn't make us more fulfilled," Dr West said.
"So long as there's a trend to work these really long hours you'll continue to see the plateauing and decline of people's wellbeing."
Dr West said almost a third of Australian full-time workers worked more than 48 hours a week and 30 per cent worked 50 hours or more.
After analysing a range of studies over the past few years, Dr West, who has published her findings in the Australian Law Reform Commission Journal, says the idea of a six-hour day is not a fantasy.
"I don't see any reason why it can't realistically happen," she said.
"It's going to require a lot of structural reform, but I think the time is ripe for addressing it as an issue."
She said the concept of the four- to six-hour working day - originally flagged by economist John Maynard Keynes in the early 1900s - would even help productivity.
But with competitiveness and the quest to "outdo one another" ingrained in society, most people weren't convinced that working less would make them happier, she said.
Dr West's research shows most people would rather work longer hours and have more money than have extra leisure and family time.
She said people who don't have money and who don't value work as their number one priority often risked being ostracised, or dubbed as lazy.
"It's difficult to be someone who places priority on leisure if you're surrounded by people who just care about money, or care about it more than other things," Dr West said.
For now, only a select privileged group with alternatives such as job sharing arrangements could afford the shorter hours, she said.
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Thursday, August 10, 2006
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GM To Debut Hybrid Full-Sized Trucks in Fall '07.
General Motors is planning a fall 2007 launch for its highly anticipated so-called "dual-mode" or two-mode gas/electric hybrid version of the 2007 Chevrolet Silverado and GMC Sierra full-size pickup trucks.
Company insiders tell Inside Line the hybrid version of the trucks will see a 25 percent improvement in fuel economy over the conventional trucks, with a combined city/highway fuel economy rating of 25 mpg. The hybrid trucks will also be outfitted with a new V8 engine with an unspecified displacement that makes approximately 365 horsepower and 350 pound-feet of torque.
Both the Chevrolet Silverado and GMC Sierra are capable of using the new hybrid system. It is unclear which truck will be the first to get the hybrid system — or whether both will get it at the same time. However, because of the hybrid's anticipated expense — at least $3,000 more than the gas-powered versions of the trucks — GM may be leaning toward introducing it first in the GMC-brand trucks, which are aimed at a more affluent audience.
GM's dual-mode hybrid trucks will be equipped with the new V8 and two electric motors that control two planetary gearsets. Another key piece of equipment will be a fuel-optimization computer. "Dual mode" refers to the hybrid's transmission setup, which allows the truck to shift between a conventional 4-speed automatic transmission and a continuously variable transmission. The shifting between transmission modes is done with the help of the onboard fuel-optimization computer, which makes split-second calculations as to which transmission mode will be the best for conserving fuel. The work is done automatically, with no buttons to push by the driver.
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Sunday, August 06, 2006
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"Anti-stupid" pill tested on mice.
A German scientist has been testing an "anti-stupidity" pill with encouraging results on mice and fruit flies, Bild newspaper reported on Saturday.
It said Hans-Hilger Ropers, director at Max-Planck-Institute for Molecular Genetics in Berlin, has tested a pill thwarting hyperactivity in certain brain nerve cells, helping stabilise short-term memory and improve attentiveness.
"With mice and fruit flies we were able to eliminate the loss of short-term memory," Ropers, 62, is quoted saying in the German newspaper, which has dubbed it the "world's first anti-stupidity pill."
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Saturday, August 05, 2006
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MIT researchers watch brain in action.
For the first time, scientists have been able to watch neurons within the brain of a living animal change in response to experience.
Thanks to a new imaging system, researchers at the Picower Institute for Learning and Memory have gotten an unprecedented look into how genes shape the brain in response to the environment. Their work is reported in the July 28 issue of Cell.
"This work represents a technological breakthrough," said first author Kuan Hong Wang, a research scientist at the Picower Institute who will launch his own laboratory at the National Institute of Mental Health in the fall. "This is the first study that demonstrates the ability to directly visualize the molecular activity of individual neurons in the brain of live animals at a single-cell resolution, and to observe the changes in the activity in the same neurons in response to the changes of the environment on a daily basis for a week."
This advance, coupled with other brain disease models, could "offer unparalleled advantages in understanding pathological processes in real time, leading to potential new drugs and treatments for a host of neurological diseases and mental disorders," said Nobel laureate Susumu Tonegawa, a co-author of the study.
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Friday, August 04, 2006
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How Australia got hot for solar power.
It's a dead-calm antipodean winter's day, the silence of this vast ranch called Tapio Station broken only by the cry of a currawong bird. Davey, chief executive of Melbourne renewable-energy company EnviroMission, aims to break ground here early next year on the world's first commercial "solar tower" power station.
"The tower will be over there," Davey says, pointing to a spot a mile distant where a 1,600-foot structure will rise from the ocher-colored earth. Picture a 260-foot-diameter cylinder taller than the Sears Tower encircled by a two-mile-diameter transparent canopy at ground level. About 8 feet tall at the perimeter, where Davey has his feet planted, the solar collector will gradually slope up to a height of 50 to 60 feet at the tower's base.
Acting as a giant greenhouse, the solar collector will superheat the air with radiation from the sun. Hot air rises, naturally, and the tower will operate as a giant vacuum. As the air is sucked into the tower, it will produce wind to power an array of turbine generators clustered around the structure.
The result: enough clean, green electricity to power some 100,000 homes without producing a particle of pollution or a wisp of planet-warming gases.
"We're aiming to be competitive with the coal people," says Davey, 60. "We're filling a gap in the renewable-energy market that has never been able to be filled before."
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With a solar tower, there's no fuel to dig out of the ground, transport, or dispose of, no smog, no scarred landscapes from open-pit mining. The sun rises every day and is not subject to embargoes, geopolitics, or commodity markets.
And once the solar tower's capital costs are paid off, the price of producing electricity should drop dramatically, as operating and maintenance costs are expected to be minimal. Despite its monolithic scale, the technology behind the tower is based on an elemental scientific truth: Hot air rises. The solar tower's only moving parts are its turbines.
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But out at Tapio Station, Davey insists that the solar tower will be built whether or not the government gives EnviroMission $75 million. "This used to be a dream," he says, staring out at the horizon where the tower will rise. "Then it became a concept. Now it's becoming reality."
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Thursday, August 03, 2006
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No head required for 20-brained bot.
Humans are lost without their heads, but not M-TRAN. The robot, made of 20 independent modules that each have their own "brain", can lose any of its body parts without breaking down.
The modules of M-TRAN, which was developed by the Intelligent Systems Research Institute in Tsukuba, Japan, consist of two blocks connected by a flexing joint, powered by electric motors. Four processors in the two blocks enable each module to operate independently, and hooks allow them to latch onto each other. These hooks also relay signals, so that modules can coordinate to change the robot's overall shape.
Previous modular robots have formed four-legged walkers, worms or wheels, but unlike M-TRAN, they were unable to function without an external computer or central brain module. Watch videos of earlier M-TRAN versions here.
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Wednesday, August 02, 2006
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When Rene Descartes said, "I think, therefore I am," the philosopher probably didn't imagine a stamp-sized clump of rat neurons grown in a dish, hooked to a computer.
For years, scientists have learned about brain development by watching the firing patterns of lab-raised brain cells. Until recently, though, the brains-in-a-dish couldn't receive information. Unlike actual gray matter, they could only send signals.
Scientists at the Georgia Institute of Technology figured they could learn more from neuron clumps that acted more like real brains, so they've developed "neurally controlled animats" -- a few thousand rat neurons grown atop a grid of electrodes and connected to a robot body or computer-simulated virtual environment.
In theory, animats seem to cross the line from mass of goo to autonomous brain. But Steve Potter, a neuroscientist and head of the Georgia Tech lab where the animats were created, said his brain clumps won't be reciting French philosophy anytime soon.
"Our goal is not to get something as conscious as a person," he said. "We're studying basic mechanisms of learning and memory." The researchers are focusing on how groups of individual cells interact and change when stimulated.
Rather than create a sentient being, the goal of the work is to learn about the earliest human brain development, according to Daniel Wagenaar, a California Institute of Technology neuroscientist who worked with Potter on the animat.
"When someone is born, they're still not able to control much of their behavior," Wagenaar said. "Somehow this system has to learn to control a body. Part of that comes from interactions with environment. We hope to get, at the very simple level of small nervous system, some insight into how that occurs."
The scientists rely on these models because no technology exists to watch live human brain cells in real-time action.
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The first generation of animats performed simple tasks. The virtual mouse tended to move in one direction (right). A dish-brain-controlled robot did manage to stay away from a moving target -- impressive-sounding perhaps but not particularly complicated. A robotic arm holding a set of pens and attached to a clump of neurons created art -- albeit in the eye of the beholder.
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"Since our cultured networks are so interconnected, they have some sense of what is going in themselves," he said. "We can also feed their activity back to them, to mediate their 'sense of self.'"
The next phase of animats will likely have an even keener sense of self.
"In the next wave, we hope to sequence behaviors." Potter said. "The sensory input resulting from one behavior will trigger the next appropriate behavior." In other words, he hopes the animats will learn.
And if consciousness is a function of complexity, what would happen if a whole bunch of dish-brains were hooked together? Right now, Potter said, the biggest obstacle to trying is the $60,000 price tag of each "rig."
"That's the present limit," he said. "If we had a rich patron, I would love to get more rigs to do some 'social networks' experiments."
Potter hopes his research will eventually lead to better neural prosthetics, understanding of neural pathologies and even artificial intelligence. As for consciousness, he said, "I don't think it will get that far. But I'd love to be proven wrong."
Nano-imaging techniques will make possible real-time analysis of neuro-molecular level events in the human brain. The brain imaging bottleneck will be broken around 2015.
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Tuesday, August 01, 2006
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US scientists have developed an anti-obesity vaccine that significantly slowed weight gain and cut body fat in animals.
Mature male rats that received the jab ate normally yet gained less weight and had less body fat, reports the Daily Telegraph.
The vaccine, described by an American team in the Proceedings of the National Academy of Sciences, may be especially important to stop "yo-yo dieting".
The vaccine acts against ghrelin, a naturally occurring hormone that helps to regulate energy balance in the body.
Prof Kim Janda of the Scripps Research Institute, California, said: "Our study is the first published evidence proving that preventing ghrelin from reaching the central nervous system can produce a desired reduction in weight gain."
According to the World Health Organization, about one billion people worldwide are overweight or obese.
Prof Janda told The Daily Telegraph: "We could speed quickly into human trials, maybe in a year, but we are going to be more cautious."
Researchers are reporting progress toward what would be a dream come true for many Americans: a vaccine to prevent obesity.
The target of this vaccine is ghrelin, a recently discovered hormone that decreases energy expenditure and fat breakdown. Scientists at the Scripps Research Institute in California reported in this week's issue of the Proceedings of the National Academy of Sciences that they have developed a way to make the immune system produce antibodies that attack ghrelin, and that rats given the vaccine ate normally but lost weight.
"We have enabled the immune system to recognize a molecule that it ordinarily won't recognize," explained study author Kim D. Janda, a professor of chemistry at Scripps.
The immune system thus produced antibodies that bound to and deactivated ghrelin, just as vaccines against diseases caused by bacteria or viruses bind to and inactivate them.
Mice given shots of the vaccine ate just as much as untreated mice but had "about a 20 or 30 percent reduction in weight gain," Janda said.
...
His best guess is that a first human trial is "about two years" away. The Scripps group is looking to link up with a major pharmaceutical company to help develop a usable vaccine, Janda said.
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